Professor Holly V. LEWIS



Clinical Assistant Professor (Part-time) MBBCh; PhD; LMCHK; FRCOG; FHKCOG; FHKAM (O&G) |
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Department of O&G, Queen Mary Hospital | |
(852)-2255-4517 | |
(852)-2855-0947 | |
https://orcid.org/0000-0001-8839-9404 |
Research Interests
- Prevention of preterm birth
- Labour Ward Management
- Medical Education
Publications
2024
- Kundu S, Dos Santos Correia G, Lee YS, Ng S, Sykes L, Chan D, Lewis H, Brown RG, Kindinger L, Dell A, Feizi T, Haslam SM, Liu Y, Marchesi JR, MacIntyre DA, Bennett PR. Secretor status is a modifier of vaginal microbiota-associated preterm birth risk. Microb Genom. 2024 Dec;10(12):001323. doi: 10.1099/mgen.0.001323. PMID: 39630497; PMCID: PMC11616779.
2023
- Ng VWY, Seto MTY, Lewis H, Cheung KW. A prospective, double-blinded cohort study using quantitative fetal fibronectin testing in symptomatic women for the prediction of spontaneous preterm delivery. BMC Pregnancy Childbirth. 2023 Apr 4;23(1):225. doi: 10.1186/s12884-023-05543-3
- Katherine Mountain, David MacIntyre, Denise Chan, Alice Hyde, James Pasint-Magyar, Yun Lee, Richard Brown, Anna David, Anne Dell, Ten Feizi, Stuart Haslam, Yan Liu, Holly Lewis, Jane Norman, Sarah Stock, Tiong Teoh, Vasso Terzidou, Samit Kundu, Phillip Bennett, Lynne Sykes, ABO blood group antigens and preterm birth risk, Journal of Reproductive Immunology, 2023, doi.org/10.1016/j.jri.2023.104083
2022
- Denise Chan, Phillip R. Bennett, Yun S. Lee, Samit Kundu, T. G. Teoh, Malko Adan, Saqa Ahmed, Richard G. Brown, Anna L. David, Holly V. Lewis, Belen Gimeno-Molina, Jane E. Norman, Sarah J. Stock, Vasso Terzidou, Pascale Kropf, Marina Botto, David A. MacIntyre & Lynne Sykes. Microbial-driven preterm labour involves crosstalk between the innate and adaptive immune response. Nat Commun 13, 975 (2022). https://doi.org/10.1038/s41467-022-28620-1
2021
- Pamela Pruski, Goncalo D. S. Correia, Holly V. Lewis, David A. MacIntyre et al. (2021) Direct on-swab metabolic profiling for rapid assessment of vaginal microbiome: host interactions during pregnancy and preterm birth. Nature Medicine
2020
- Zarasvand S, Bayar E, Adan M, Mountain K, Lewis H, Joash K, Teoh TG, Bennett PR, Das S, Sykes L. Rapid quality improvement in a preterm birth clinic care pathway during the COVID-19 pandemic. BMJ Open Qual. 2020 Dec;9(4):e001049. doi: 10.1136/bmjoq-2020-001049. PMID: 33372041; PMCID: PMC7771216.
2018
- Pruski P, Lewis HV, Lee YS, Marchesi JR, Bennett PR, Takats Z, MacIntyre DA. Assessment of microbiota:host interactions at the vaginal mucosa interface. Methods. 2018 Oct 1;149:74-84. doi: 10.1016/j.ymeth.2018.04.022. Epub 2018 Apr 27. PMID: 29705211.
- Brown RG, Al-Memar M, Marchesi JR, Lee YS, Smith A, Chan D, Lewis H, Kindinger L, Terzidou V, Bourne T, Bennett PR, MacIntyre DA. Establishment of vaginal microbiota composition in early pregnancy and its association with subsequent preterm prelabor rupture of the fetal membranes. Transl Res. 2019 May;207:30-43. doi: 10.1016/j.trsl.2018.12.005. Epub 2018 Dec 27. PMID: 30633889; PMCID: PMC6489901.
2017
- H Lewis, P Pruski, L Kindinger, R Brown, Y Lee, P Inglese, P Bennett, Z Takats, DA MacIntyre. "Desorption electrospray ionisation mass spectrometry permits identification of vaginal mucosal metabolome signatures associated with preterm birth risk." BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. Vol. 124. 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY, 2017.
- Pruski P, MacIntyre DA, Lewis HV, Inglese P, Correia GD, Hansel TT, Bennett PR, Holmes E, Takats Z. Medical Swab Analysis Using Desorption Electrospray Ionization Mass Spectrometry: A Noninvasive Approach for Mucosal Diagnostics. Anal Chem. 2017 Feb 7;89(3):1540-1550. doi: 10.1021/acs.analchem.6b03405. Epub 2017 Jan 11. PMID: 28208268.