Professor Ernest H.Y. NG 吳鴻裕教授

Professor Ernest H.Y. NG hku_logo qmh_logo

Clinical Professor

MBBS; MD (HK); FRCOG; FHKAM (O&G)

location Department of O&G, Queen Mary Hospital
phone (852)-2255-4517
fax (852)-2855-0947
email nghye@hku.hk
email HKU Scholars Hub
email https://orcid.org/0000-0002-7688-4557
Research Interests
  • Assisted reproduction methods
  • Assessment of ovarian reserve 
  • Evaluation of endometrial receptivity 
  • Use of three-dimensional ultrasound in reproduction medicine
  • Use of acupuncture in reproductive medicine
  • Stem cell
PubMed Search

Author Name: Ng EH

Publications
2024
2023
2022
  • Ko K.Y.J., Shi J., Li R.H.W., Yeung W.S.B. and Ng E.H.Y., 100 YEARS OF VITAMIN D: Effect of serum vitamin D level before ovarian stimulation on the cumulative live birth rate of women undergoing in vitro fertilization: a retrospective analysis, Endocrine Connections. 2022, 11.
  • Cheung KW, Seto MTY, Wang W, Ng CT, To WWK, Ng EHY. Trend and causes of maternal death, stillbirth and neonatal death over seven decades in Hong Kong. Lancet Reg Health West Pac. 2022 Jul 6;26:100523. doi: 10.1016/j.lanwpc.2022.100523. PMID: 35833208; PMCID: PMC9272372.
  • Ng Y.T.D., Lo A., So E.W.S., Wong G.C.Y., Li R.H.W., Wong Y.Y. and Ng E.H.Y., A randomized controlled study of acupuncture for pain relief during first trimester surgical termination of pregnancy performed under local analgesia, Acupuncture in Medicine. 2022, 40, 224-231.
  • FERNANDO T.S.R., CHEN X., Cheng K.W., Wong B.P.C., Qi S., Jiang L., Kodithuwakku Kankanamge S.P.K., Ng E.H.Y., Yeung W.S.B. and Lee C.K.F., ACE inhibitors on ACE1, ACE2, and TMPRSS2 expression and spheroid attachment on human endometrial Ishikawa cells, Reproductive Biology. 2022, 22, 100666.
  • Wong E., Ng E.H.Y., Li R.H.W. and Ko K.Y.J., Comparing the intercycle variation of serum anti‐Mullerian hormone and antral follicle count measurements over four consecutive menstrual cycles, Clinical Endocrinology. 2022. http://dx.doi.org/10.1111/cen.14843
  • Cao D., Chan R.W.S., Ng E.H.Y., Gemzell Danielsson E.K.M. and Yeung W.S.B., Correction: Single-cell RNA sequencing of cultured human endometrial CD140b+CD146+ perivascular cells highlights the importance of in vivo microenvironment, Stem Cell Research & Therapy. 2022, 13.
  • Wen Q., Hu M., Lai M., Li J., Hu Z., Quan K., Liu J., Liu H., Meng Y., Wang S., Wen X., Yu C., Li S., Huang S., Zheng Y., Lin H., Liang X., Lu L., Mai Z., Zhang C., Wu T., Ng E.H.Y., Stener-Victorin E. and Ma H., Effect of acupuncture and metformin on insulin sensitivity in women with polycystic ovary syndrome and insulin resistance: a three-armed randomized controlled trial, Human Reproduction. 2022, 37, 542-552.
  • CHEN X., FERNANDO T.S.R., Lee C.Y.L., Yeung W.S.B., Ng E.H.Y., Li R.H.W. and Lee C.K.F., High-Throughput In Vitro Screening Identified Nemadipine as a Novel Suppressor of Embryo Implantation, International Journal of Molecular Sciences. 2022, 23, 5073.
  • BAI K., Lee C.L., Liu X., LI J., Cao D., Zhang L., Hu D., Li H., Hou Y., Xu Y., Kan S.Y.A., Cheung K.W., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., Human placental exosomes induce maternal systemic immune tolerance by reprogramming circulating monocytes, Journal of Nanobiotechnology. 2022, 20.
  • ZHANG S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Hypoxia Regulates the Self-Renewal of Endometrial Mesenchymal Stromal/Stem-like Cells via Notch Signaling, International Journal of Molecular Sciences. 2022, 23, 4613.
  • Zhao Y., ZHANG Y., Liu D., Feng H., Wang X., Su J., Yao Y., Ng E.H.Y., Yeung W.S.B., Li R.H.W., Rodrigues-Wallberg K.A. and Liu K., Identification of curcumin as a novel potential drug for promoting the development of small ovarian follicles for infertility treatment, PNAS Nexus. 2022.
  • Guo W., Li R.H.W., Yang Z., Zeng L., Yang R., Qiao J., Li R. and Ng E.H.Y., Live birth after letrozole as an adjunct to follicle-stimulating hormone versus follicle-stimulating hormone alone for ovarian stimulation in in vitro fertilisation cycles—study protocol for a randomised controlled trial, Trials. 2022, 23.
  • Meng W., Lin W.L., Yeung W.F., Zhang Y., Ng E.H.Y., Lee E.Y.P., Zhang Z., Rong J. and Lao L., Randomized double-blind trial comparing low dose and conventional dose of a modified traditional herbal formula Guizhi Fuling Wan in women with symptomatic uterine fibroids, Journal of Ethnopharmacology. 2022, 283, 114676.
  • Mok Y.K.S., Cheung K.W., Wang W., Li R.H.W., Shek W.M.N. and Ng E.H.Y., The effects of not having continuous companion support during labour on pregnancy and neonatal outcomes during the COVID-19 pandemic, Midwifery. 2022, 108, 103293.
  • Ko K.Y.J., Shi J., Li R.H.W., Yeung W.S.B. and Ng E.H.Y., 100 YEARS OF VITAMIN D: Effect of serum vitamin D level before ovarian stimulation on the cumulative live birth rate of women undergoing in vitro fertilization: a retrospective analysis, Endocrine Connections. 2022, 11.
  • Zhang S, Chan RWS, Ng EHY, Yeung WSB. The Role of Notch Signaling in Endometrial Mesenchymal Stromal/Stem-like cells Maintenance. Communications Biology. 2022.
  • Li X, Kodithuwakku SP, Chan RWS, Yeung WSB, Yao Y, Ng EHY, Chiu PCN, Lee CL. Three-dimensional culture models of human endometrium for studying trophoblast-endometrium interaction during implantation. Reprod Biol Endocrinol. 2022 Aug 13;20(1):120.
2021
  • Cao D., Shi F., Guo C., Liu Y., Lin Z., Zhang J., Li R.H.W., Yao Y., Liu K., Ng E.H.Y., Yeung W.S.B. and Wang T., A pathogenic DMC1 frameshift mutation causes nonobstructive azoospermia but not primary ovarian insufficiency in humans, Molecular Human Reproduction. 2021, 27. http://dx.doi.org/10.1093/molehr/gaab058
  • Lam MT, Lock CHY, Lam KKW, Li RHW, Yeung WSB, Ng EHY (2021). A prospective study of variations in conventional semen parameters among local andrology laboratories. Journal of Man’s Health. Vol.17,Issue 2,April 2021 pp.95-100
  • Lai S.F., Choi S.N.S., Ho Y.B.W., Hung W.Y.W., Lam M.T., Law T.S.M., Ng Y.T.D., Tam C.T., Wan S.F., Li R.H.W., Leung W.C., Yeung W.S.B. and Ng E.H.Y., A questionnaire survey on patients’ willingness to pay with reference to the waiting time of public in-vitro fertilization treatment in Hong Kong, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2021, 258, 430-436. http://dx.doi.org/10.1016/j.ejogrb.2021.01.026
  • Lam KKW, Wong JYY, Cheung TM, Li RHW, Ng EHY, Yeung WSB (2021). A retrospective analysis of artificial oocyte activation in patients with low or no fertilization in intracytoplasmic sperm injection cycles. Journal of Obstetrics and Gynaecology. Online ahead of print
  • Tong Y.W., Lo S.T.S., Fung B.W.K., Cameron S.T., Ng E.H.Y. and Li R.H.W., Acceptability of different mechanisms of action of contraception in women: a questionnaire survey, BMJ Sexual & Reproductive Health. 2021, bmjsrh-2021-201110. http://dx.doi.org/10.1136/bmjsrh-2021-201110
  • Fan H., FERNANDO T.S.R., Jiang L., Wang Z., Kodithuwakku Kankanamge S.P.K., Wong C.K.C., Ng E.H.Y., Yeung W.S.B. and Lee C.K.F., Bisphenol A Analogues Suppress Spheroid Attachment on Human Endometrial Epithelial Cells through Modulation of Steroid Hormone Receptors Signaling Pathway, Cells. 2021, 10, 2882. http://dx.doi.org/10.3390/cells10112882
  • Ko K.Y.J., Kan A., Leung P., Lee V.C.Y., Li R.H.W., Ledger W. and Ng E.H.Y., Comparison of the number of oocytes obtained after ovarian stimulation between Chinese and Caucasian women undergoing in vitro fertilization using a standardized stimulation regime, Journal of Ovarian Research. 2021, 14. http://dx.doi.org/10.1186/s13048-021-00928-4
  • Zhao Y., Feng H., ZHANG Y., Zhang J., Wang X., Liu D., Wang T., Li R.H.W., Ng E.H.Y., Yeung W.S.B., Rodriguez-Wallberg K.A. and Liu K., Current Understandings of Core Pathways for the Activation of Mammalian Primordial Follicles, Cells. 2021, 10, 1491. http://dx.doi.org/10.3390/cells10061491
  • FERNANDO T.S.R., Kottawatta K.S.A., JIANG L., CHEN X., Cheng K.W., Wong B.P.C., Ng E.H.Y., Yeung W.S.B. and Lee C.K.F., Differential expression of protein disulfide isomerase (PDI) in regulating endometrial receptivity in humans, Reproductive Biology. 2021, 21, 100498. http://dx.doi.org/10.1016/j.repbio.2021.100498
  • Fernando S.R., Lee C.L., Wong B.P.C., Cheng K.W., Lee C.Y.L., Chan M.C., Ng E.H.Y., Yeung W.S.B. and Lee C.K.F., Expression of membrane protein disulphide isomerase A1 (PDIA1) disrupt a reducing microenvironment in endometrial epithelium for embryo implantation, Experimental Cell Research. 2021, 405, 112665. http://dx.doi.org/10.1016/j.yexcr.2021.112665
  • Fernando SR, Kottawatta KSA, Jiang L, Chen X, Cheng KW, Wong BP, Ng EH, Yeung WS, Lee KF. Differential expression of protein disulfide isomerase (PDI) in regulating endometrial receptivity in humans. Reprod Biol. 2021 Jun;21(2):100498. doi: 10.1016/j.repbio.2021.100498. Epub 2021 Mar 4. PMID: 33677360.
  • Fernando SR, Lee CL, Wong BP, Cheng KW, Lee YL, Chan MC, Ng EH, Yeung WS, Lee KF. Expression of membrane protein disulphide isomerase A1 (PDIA1) disrupt a reducing microenvironment in endometrial epithelium for embryo implantation. Exp Cell Res. 2021 Jun 8;405(2):112665. doi: 10.1016/j.yexcr.2021.112665. Epub ahead of print. PMID: 34111473.
  • Ko JKY, Lam KKW, Cheng HHY, Lui MW, Yung SSF, Li RHW, Lau EYL, Ho PC, Yeung WSB, Ng EHY (2021). Fertility Preservation Programme in a Tertiary-Assisted Reproduction Unit in Hong Kong. Fertility & Reproduction. Vol. 03, No. 03, pp. 94-100.
  • Lam M.T., Li R.H.W. and Ng E.H.Y., Impact of Endometrial Thickness and Volume Compaction on the Live Birth Rate Following Fresh Embryo Transfer of In Vitro Fertilization, Journal of Ultrasound in Medicine. 2021. http://dx.doi.org/10.1002/jum.15830
  • Cheung K.W., Seto T.Y.M., Tsui P.M., So P.L., Wong D., Kong C.W., Wang W. and Ng E.H.Y., Knowledge, perception and expectation of management of hepatitis B infection among pregnant hepatitis B carriers in Hong Kong
  • Cheung K.W., Optimal Management of Pregnant Hepatitis B Carriers to Achieve Complete Eradication of Hepatitis B Infection in Hong Kong, Hong Kong Medical Diary. 2021, 26(3), 7-9.
  • BAI K., LI X., ZHONG J., Ng E.H.Y., Yeung W.S.B., Lee C.L. and Chiu C.N., Placenta-Derived Exosomes as a Modulator in Maternal Immune Tolerance During Pregnancy, Frontiers in Immunology. 2021, 12. http://dx.doi.org/10.3389/fimmu.2021.671093
  • Lo S.T.S., Li R.H.W., Kok W.M., Wong C.Y.G., Ng E.H.Y. and Chan C.H.Y., Sexual function and quality of life in Chinese couples undergoing assisted reproductive treatment: a prospective cohort study, Human Fertility. 2021, 1-13. http://dx.doi.org/10.1080/14647273.2020.1871518
  • Leung ETY, Lee CL, Tian X, Lam KKW, Li RHY, Ng EHY, Yeung WSB, Chiu PCN (2021). Simulating nature in sperm selection for assisted reproduction. Nature Review Urology. Online ahead of print.
  • Cao D, Chan RWS, Ng EHY, Gemezell-Danielsson K, Yeung WSB. Single-cell RNA sequencing of cultured human endometrial CD140b+CD146+ perivascular cells highlight the importance of in vivo microenvironment. Stem Cell Research & Therapy, 2021, 12(1):306. 2021
  • WANG Z., Kottawatta K.S.A., Kodithuwakku S.P., Fernando T.S., Lee C.Y.L., Ng E.H.Y., Yeung W.S.B. and Lee C.K.F., The fungicide Mancozeb reduces spheroid attachment onto endometrial epithelial cells through downregulation of estrogen receptor β and integrin β3 in Ishikawa cells, Ecotoxicology and Environmental Safety. 2021, 208, 111606. http://dx.doi.org/10.1016/j.ecoenv.2020.111606
  • Li M., ZHENG J., Li G., Lin Z., LI D., Liu D., Feng H., Cao D., Ng E.H.Y., Li R.H.W., Han C., Yeung W.S.B., Chow L.T., Wang H. and Liu K., The male germline-specific protein MAPS is indispensable for pachynema progression and fertility, Proceedings of the National Academy of Sciences. 2021, 118, e2025421118. http://dx.doi.org/10.1073/pnas.2025421118
  • Lin H., Liu M., Zhong D., Ng E.H.Y., Liu J., Li J., Shi Y., Zhang C., Wen X., Mai Z., Ou M. and Ma H., The Prevalence and Factors Associated With Anxiety-Like and Depression-Like Behaviors in Women With Polycystic Ovary Syndrome, Frontiers in Psychiatry. 2021, 12. http://dx.doi.org/10.3389/fpsyt.2021.709674
  • Chan M.K.D., Cheung K.W., Ko K.Y.J., Yung S.F.S., Lai S.F., Lam M.T., Ng Y.T.D., Lee V.C.Y., Li R.H.W. and Ng E.H.Y., Use of oral progestogen in women with threatened miscarriage in the first trimester: a randomized double-blind controlled trial, Human Reproduction. 2021, 36, 587-595. http://dx.doi.org/10.1093/humrep/deaa327
2020
  • Cao MZ, Chan RWS, Cheng FHC, Li J, Li T, Pang RTK, Lee CL, Li RHW, Ng EHY, Chiu PCN, Yeung WSB. Myometrial cells stimulate self-renewal of endometrial mesenchymal stem-like cells through WNT5A/β-catenin signalling. Stem Cells. 2019. 37(1): 1455-66
  • Xu S., Chan R.W.S., LI T., Ng E.H.Y. and Yeung W.S.B., Understanding the regulatory mechanisms of endometrial mesenchymal stem-like cells during menstruation., Stem Cell Research & Therapy . 2020, 11. http://dx.doi.org/10.1186/s13287-020-01750-3
  • Fan H, Jiang L, Lee YL, Wong CKC, Ng EHY, Yeung WSB, Lee KF. Bisphenol compounds regulate decidualized stromal cells in modulating trophoblastic spheroid outgrowth and invasion in vitro†. Biol Reprod. 2020 Mar 13;102(3):693-704. doi: 10.1093/biolre/ioz212. PMID: 31742322.
  • Vijayan M, Lee CL, Wong VHH, Wang X, Bai K, Wu J, Koistinen H, Seppälä M, Lee KF, Yeung WSB, Ng EHY, Chiu PCN. Decidual glycodelin-A polarizes human monocytes into a decidual macrophage-like phenotype through Siglec-7. J Cell Sci. 2020 Jul 23;133(14):jcs244400. doi: 10.1242/jcs.244400. PMID: 32513821.
  • Chow, J., Cheng, H., Lau, E., Yeung, W., & Ng, E. (2020). Distinguishing between carrier and noncarrier embryos with the use of long-read sequencing in preimplantation genetic testing for reciprocal translocations. Genomics, 112(1), 494-500​

  • Wang X, Lee CL (Co-first author), Vijayan M, Yeung WSB, Ng EHY, Wang X, Li HWR, Zhang Y, Chiu PCN. Adrenomedullin insufficiency alters macrophage activities in pro-inflammatory conditions: a pathophysiologic explanation of tubal ectopic pregnancy. Mucosal Immunology.
2019
  • Chow JFC, Cheng HHY, Lau EYL, Yeung WSB, Ng EHY. Selective transfer of euploid noncarrier embryos with the use of long-read sequencing in preimplantation genetic testing or reciprocal translocation. Reproductive biomedicine online. 2019;39:e14-e5.
  • Chow JFC, Cheng HHY, Lau EYL, Yeung WSB, Ng EHY. High-resolution mapping of reciprocal translocation breakpoints using long-read sequencing. MethodsX. 2019;6:2499-503.
  • Chow JFC, Yeung WSB, Lee VCY, Lau EYL, Ng EHY. PGT-SR using NGS and haplotype analysis with microsatellite markers to distinguish normal from balanced Robertsonian ranslocation carrier embryo. Reproductive biomedicine online. 2019;38:e21-e2.
  • Cao M, Chan RWS, Cheng FHC, Xua S, Li J, Li T, Pang RTK, Lee CL, Li RHW, Ng EHY, Chiu PCN, Yeung WSB. Myometrial cells stimulate self-renewal of endometrial mesenchymal stem-like cells through WNT5A/β-catenin signaling. Stem cells. 2019. 37(11):1455–1466.
  • Chan H.S.S., Li R.H.W., Lee V.C.Y., Tang M.H.Y. and Ng E.H.Y., Knowledge, Attitude And Ethical Consideration Of Chinese Couples Requesting Preimplantation Genetic Testing In Hong Kong., J Obstet Gynaecol Res. 2019. http://dx.doi.org/10.1111/jog.13940

  • Chen Z.Q./., Wang Y., Ng E.H.Y., Zhao M., Pan J.P., Wu H.X. and Teng X.M., A randomized triple blind controlled trial comparing the live birth rate of IVF following brief incubation versus standard incubation of gametes, Human Reproduction. 2019, 34, 100-108. http://dx.doi.org/10.1093/humrep/dey333

  • Chan C.H.Y., Lau B.H.P., Wong Q.S., Tam M.Y.J., So Y.K.G., Leung H.T., Fung Y.L., Chan C.L.W., Li R.H.W. and Ng E.H.Y., Comparing the effectiveness of I-BMS-informed self-help interventions in alleviating psychosocial distress for women awaiting the outcome of IVF treatment, In: Lee Geok Ling, Asia Pacific Journal of Social Work and Development. 2019. http://dx.doi.org/10.1080/02185385.2019.1578684

  • Cheng I.S.C., LI R., Leung G.P.H., Li S.L., Kong M., Lao L., Zhang Z., Lin W.L., Ng E.H.Y., Rong J., Chen J., Su J., Zhang Y. and Meng W., Application of UPLC?MS/MS to simultaneously detect four bioactive compounds in the tumour?shrinking decoction (FM1523) for uterine fibroids treatment, Phytochemical Analysis. 2019. http://dx.doi.org/10.1002/pca.2827

  • Cheung K.W., Seto T.Y.M., So P.L., Wong D., Mak S.L.A., Lau W.L., Wang W., Kan S.Y.A., Lee C.P. and Ng E.H.Y., Optimal timing of hepatitis B virus DNA quantification and clinical predictors for higher viral load during pregnancy, Acta Obstetricia et Gynecologica Scandinavica. 2019, 98, 1301-1306. http://dx.doi.org/10.1111/aogs.13631

  • Cheung K.W., Seto T.Y.M., Wong S., Mak S.L.A., So P.L., Lau W.L., Wang W., Kan S.Y.A., Lee C.P. and Ng E.H.Y., Pattern and predictors of medical care received by hepatitis B carriers during pregnancy and after delivery, Public Health. 2019, 168, 36-42. http://dx.doi.org/10.1016/j.puhe.2018.12.008

  • Cheung K.W., Seto T.Y.M., So P.L., Wong D., Mak S.L.A., Lau W.L., Lau W.L., Kan S.Y.A., Lee C.P. and Ng E.H.Y., The effect of rupture of membranes and labour on the risk of hepatitis B vertical transmission: Prospective multicentre observational study, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2019, 232, 97-100. http://dx.doi.org/10.1016/j.ejogrb.2018.11.017

  • Cheung K.W., Seto T.Y.M. and Ng E.H.Y., What is the optimal timing of antiviral treatment in pregnant hepatitis B carriers with extremely high viral load?, Acta Obstetricia et Gynecologica Scandinavica. 2019. http://dx.doi.org/10.1111/aogs.13721

  • Lau B.H.P., Yao H., Tam M.Y.J., Chan C.L.W., Ng E.H.Y. and Chan C.H.Y., Gratitude in infertility: A cross-sectional examination of dispositional gratitude in coping with infertility-related stress in women undergoing in vitro fertilization (IVF), Human Reproduction Open. 2019, 1-11. http://dx.doi.org/10.1093/hropen/hoz012

  • Lee C.L., Vijayan M., Wang X., Lam K.W., Koistinen H., Seppala M., Li R.H.W., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., Glycodelin-A stimulates the conversion of human peripheral blood CD16−CD56bright NK cell to a decidual NK cell-like phenotype, Human Reproduction. 2019, 34, 689-701. http://dx.doi.org/10.1093/humrep/dey378

  • Li R.H.W., Ko K.Y.J., Lee V.C.Y., Yung S.F.S., Lau Y.L.E., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Comparing antral follicle count and serum anti?Mullerian hormone level for determination of gonadotrophin dosing in in?vitro fertilisation: a randomized trial , Ultrasound in Obstetrics & Gynecology. 2019. http://dx.doi.org/10.1002/uog.20402

  • Lui M.W.E., Yeung W.S.B., Ho P.C. and Ng E.H.Y., In vitro fertilisation in Hong Kong: the situation in 2019, Hong Kong Medical Journal. 2019. http://dx.doi.org/10.12809/hkmj198057

  • Wong H.Y.Q., Lui M.W.E., Yung S.F.S., Ko K.Y.J., Li R.H.W. and Ng E.H.Y., Randomized controlled trial of transcutaneous electrical nerve stimulation for pain relief during transvaginal oocyte retrieval using conscious sedation: study protocol for a randomized controlled trial, Trials. 2019, 20. http://dx.doi.org/10.1186/s13063-019-3227-5

2018
  • Cheung K.W., Seto T.Y.M. and Ng E.H.Y., Tenofovir to Prevent Perinatal Transmission of Hepatitis B, New England Journal of Medicine. 2018, 378: 2348-2350. http://dx.doi.org/10.1056/NEJMc1805396 (Publication No. : 293589)

  • Cheung K.W., Seto T.Y.M., Kan S.Y.A., Jalal K., Chee W.Y.Y., Wong R.M.S., Lee C.P. and Ng E.H.Y., Immunoprophylaxis Failure of Infants Born to Hepatitis B Carrier Mothers Following Routine Vaccination, Clinical Gastroenterology and Hepatology. 2018, 16: 144-145. http://dx.doi.org/10.1016/j.cgh.2017.07.013 (Publication No. : 292449)

  • Chow JF, Yeung WS, Lee VC, Lau EY, Ng EH. Evaluation of preimplantation genetic testing for chromosomal structural rearrangement by a commonly used next generation sequencing workflow. Eur J Obstet Gynecol Reprod Biol. 2018 May;224:66-73.

  • Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau Y.L.E. and Ng E.H.Y., Evaluation of preimplantation genetic testing for chromosomal structural rearrangement by a commonly used next generation sequencing workflow, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2018, 224: 66-73. http://dx.doi.org/10.1016/j.ejogrb.2018.03.013 (Publication No. : 293617)

  • Lai S.F., Li R.H.W., Yeung W.S.B. and Ng E.H.Y., Effect of paternal age on semen parameters and live birth rate of in-vitro fertilisation treatment: a retrospective analysis, Hong Kong Medical Journal. 2018. http://dx.doi.org/10.12809/hkmj177111 (Publication No. : 295766)

  • Li H.E., Li L.U., Lu X.I.A.N.G., Sun X.I.A.O.X.I. and Ng E.H.Y., Comparison of the effect of immediate versus delayed transfer following a stimulated IVF cycle on the ongoing pregnancy rate of frozen-thawed embryo transfer cycles: a study protocol for a randomised controlled trial, BMJ Open. 2018, 8: e020507. http://dx.doi.org/10.1136/bmjopen-2017-020507 (Publication No. : 293616)

  • Li J., Wu Q., Wu X.K., Zhou Z.M., Fu P., Chen X.H., Yan Y., Wang X., Yang Z.W., Li W.L., Stener-Victorin E., Legro R.S., Ng E.H.Y., Zhang H., Mol B.W.J. and Wang C.C., Effect of exposure to second-hand smoke from husbands on biochemical hyperandrogenism, metabolic syndrome and conception rates in women with polycystic ovary syndrome undergoing ovulation induction, Human Reproduction. 2018, 33: 617-625. http://dx.doi.org/10.1093/humrep/dey027 (Publication No. : 293618)

  • Ma H.L., Xie L.Z., Gao J.S., Cong J., Deng Y.Y., Ng E.H.Y., Liu J.P. and Wu X.K., Acupuncture and clomiphene for Chinese women with polycystic ovary syndrome (PCOSAct): statistical analysis approach with the revision and explanation, Trials. 2018, 19. http://dx.doi.org/10.1186/s13063-018-2942-7 (Publication No. : 296091)

  • Chan C.H.Y., Lau B.H.P., Wong Q.S., Tam M.Y.J., So Y.K.G., Leung H.T., Fung Y.L., Chan C.L.W., Li R.H.W. and Ng E.H.Y., Comparing the effectiveness of I-BMS-informed self-help interventions in alleviating psychosocial distress for women awaiting the outcome of IVF treatment, In: Lee Geok Ling, Asia Pacific Journal of Social Work and Development. 2019. http://dx.doi.org/10.1080/02185385.2019.1578684

  • Wong H.Y.Q., Li R.H.W., Lam K.S.L., Tam S., Shek C.C., Lee V.C.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Independent association of serum vitamin D with anti-Mullerian hormone levels in women with polycystic ovary syndrome, Clinical Endocrinology. 2018. http://dx.doi.org/10.1111/cen.13816 (Publication No. : 293219)

  • Wong Q.H.Y., Yeung T.W.Y., Yung S.F.S., Ko K.Y.J., Li R.H.W. and Ng E.H.Y., The effect of 12-month dehydroepiandrosterone supplementation on the menstrual pattern, ovarian reserve markers, and safety profile in women with premature ovarian insufficiency, Journal of Assisted Reproduction and Genetics. 2018, 35: 857-862. http://dx.doi.org/10.1007/s10815-018-1152-2 (Publication No. : 289307)

  • Wong QHY, Yeung TWY, Yung SSF, Ko JKY, Li HWR, Ng EHY. The effect of 12-month dehydroepiandrosterone supplementation on the menstrual pattern, ovarian reserve markers, and safety profile in women with premature ovarian insufficiency. J Assist Reprod Genet 2018.

2017
  • Chan RWS, Lee CL, Ng EH, Yeung WSB. Coculture with Macrophages enhanced the Clonogenic and Invasion Activity of Endometriotic Stromal Cells. Cell Proliferation. 2017;50:e12330.

  • Chan R.W.S., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Co-culture with macrophages enhances the clonogenic and invasion activity of endometriotic stromal cells, Cell Proliferation. John Wiley & Sons Ltd, 2017, 50: 1-9.

  • Chen C.H., Lee C.Y.L., Fong S.W., Wong C.C.Y., Ng E.H.Y. and Yeung W.S.B., Hyperglycemia impedes definitive endoderm differentiation of human embryonic stem cells by modulating histone methylation patterns, Cell and Tissue Research. 2017, 2017 Jun;368(3):563-578.

  • Chen C.H., Lee C.Y.L., Fong S.W., Wong C.C.Y., Ng E.H.Y. and Yeung W.S.B., Hyperglycemia impedes definitive endoderm differentiation of human embryonic stem cells by modulating histone methylation patterns, Cell and Tissue Research. 2017, 2017 Jun;368(3):563-578.

  • Cheung K.W., Seto M.T.Y., Kan A.S.Y., Wong D., Kou T.K.O., So P.L., Lau W.L., Jalal K., Chee Y.Y., Wong R.M.S., Lee C.P., Ng E.H.Y. (2017) Immunoprophylaxis failure of infants born to Hepatitis B carrier mothers following routine vaccination. Clin Gastroenterol Hepatol. 2017 Jul 18. pii: S1542-3565(17)30850-9. doi: 10.1016/j.cgh.2017.07.013

  • Chow JF, Yeung WS, Lee VC, lau EY, Ho PC, Ng EH. Preimplantation genetic diagnosis and screening by array comparative genomic hybridisation: experience of more than 100 cases in a single centre. Hong Kong Med J. 2017 Apr;23(2):129-33.

  • Lee VCY, Li RHW, Yeung WSB, Pak Chung HO, Ng EHY. A randomized double-blinded controlled trial of hCG as luteal phase support in natural cycle frozen embryo transfer. Hum Reprod. 2017 May 1;32(5):1130-1137.

     

  • Li HWR, Li YX, Li TT, Fan H, Ng EH, Yeung WS, Ho PC, Lee KF. Effect of ulipristal acetate and mifepristone at emergency contraception dose on the embryo-endometrial attachment using an in vitro human trophoblastic spheroid and endometrial cell co-culture model. Hum Reprod. 2017 Dec 1;32(12):2414-2422. doi: 10.1093/humrep/dex328.

  • Li J., Ng E.H., Stener-Victorin E., Hu Z., Shao X., Wang H., Li M., Lai M., Xie C., Su N., Yu C., Liu J, Wu T, Ma H. (2017) Acupuncture treatment for insulin sensitivity of women with polycystic ovary syndrome and insulin resistance: a study protocol for a randomized controlled trial. Trials. 2017 Mar 9;18(1):115.

  • Seto M.T.Y., Cheung K.W., Lo T.K., Ng E.H.Y., Pregnancy outcomes of women randomized to receive real versus placebo acupuncture on the day of fresh or frozen-thawed embryo transfer. Eur J Obstet Gynecol Reprod Biol. 2017 Nov;218:119-122.

  • Wang R., Kim B.V., Wely M.V., Johnson N.P., Costello M.F., Zhang H., Ng E.H.Y., Legro R.S., Bhattacharya S., Norman R.J. and Mol B.W.J., Treatment strategies for women with WHO group II anovulation: systematic review and network meta-analysis, British Medical Journal Open. 2017, 356: j138.

  • Wu X.K., Stener-Victorin E., Kuang H.Y., Ma H.L., Gao J.S., Xie L.Z., Hou L.H., Hu Z.X., Shao X.G., Ge J., Zhang J.F., Xue H.Y., Xu X.F., Liang R.N., Ma H.X., Yang H.W., Li W.L., Huang D.M., Sun Y., Hao C.F., Du S.M., Yang Z.W., Wang X., Yan Y., Chen X.H., Fu P., Ding C.F., Gao Y.Q., Zhou Z.M., Wang C.C., Wu T.X., Liu J.P., Ng E.H.Y., Legro R.S., Zhang H.; PCOSAct Study Group., Effect of Acupuncture and Clomiphene in Chinese Women With Polycystic Ovary Syndrome: A Randomized Clinical Trial. JAMA. 2017 Jun 27;317(24):2502-2514.

  • Xu S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Spatial and temporal characterization of endometrial mesenchymal stem-like cells activity during the menstrual cycle, Experimental Cell Research. Elsevier Inc, 2017, 350(1): 184-189.

  • Ye D., Li M., Zhang Y., Wang X., Liu H., Wu W., Ma W., Quan K., Ng E.H., Wu X., Lai M., Ma H., Cryptotanshinone Regulates Androgen Synthesis through the ERK/c-Fos/CYP17 Pathway in Porcine Granulosa Cells. Evid Based Complement Alternat Med. 2017;2017:5985703.

2016
  • Chan C.H.Y., Chan T.H.Y., Tam M.Y.J., WONG S., Ng E.H.Y. and Chan C.L.W., Preferred roles in treatment decision-making, decisional conflict and depression: A longitudinal study of Chinese women making decisions on IVF treatment, Human Reproduction. 2016, 31(Suppl 1): i348.

  • Chan C.H.Y., Lau H.P., Tam M.Y.J. and Ng E.H.Y., A longitudinal study investigating the role of decisional conflicts and regret and short-term psychological adjustment after IVF treatment failure, Human Reproduction. 2016, 31: 1-9.

  • Chan DM, Cheung KW, Yung SS, Lee VC, Li RH, Ng EH. A randomized double-blind controlled trial of the use of dydrogesterone in women with threatened miscarriage in the first trimester: study protocol for a randomized controlled trial. Trials. 2016;17(1):408.

  • Ko K.Y.J., Chai J., Lee V.C.Y., Li R.H.W., Lau Y.L.E., Ho K.L., Tam P.C., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Sperm retrieval rate and pregnancy rate in infertile couples undergoing in-vitro fertilisation and testicular sperm extraction for non-obstructive azoospermia in Hong Kong, Hong Kong Medical Journal. 2016, 22(6): 556-562.

  • Ko K.Y.J., Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Ho P.C. and Ng E.H.Y., Serum adiponectin is independently associated with the metabolic syndrome in Hong Kong, Chinese women with polycystic ovary syndrome, Gynecological Endocrinology. 2016, 32: 390-394. http://dx.doi.org/10.3109/09513590.2015.1126708

  • Lee C.L., Lam K.K., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The pleiotropic effect of glycodelin-A in early pregnancy, American Journal of Reproductive Immunology. 2016, 75(3): 290-297.

  • Lee VC, Chow JF, Lau EY, Kwong A, Leung SY, Yeung WS, Ho PC, Ng EH. 2016 Preimplantation genetic diagnosis for hereditary cancer syndrome: local experience. Hong Kong Med J. Jun; 22(3): 289-91.

  • Li J., Ng E.H.Y., Stener-Victorin E., Hu Z., Wu W., Lai M., Wu T. and Ma H., Comparison of acupuncture pretreatment followed by letrozole versus letrozole alone on live birth in anovulatory infertile women with polycystic ovary syndrome: a study protocol for a randomised controlled trial, British Medical Journal Open. 2016, 6(10): e010955.

  • Li R.H.W., Lo S.T.S., Ng E.H.Y. and Ho P.C., Efficacy of ulipristal acetate for emergency contraception and its effect on the subsequent bleeding pattern when administered before or after ovulation, Human Reproduction. 2016, 31: 1200-1207.

  • Tam M.Y.J., Chan C.H.Y., Ng E.H.Y., Chan C.L.W., WONG S., Wong W.Y. and Chan K.L., Impact of treatment decisions and significance of cultural beliefs in predicting quality of life of Chinese infertile women. Human Reproduction, Human Reproduction. 2016, 31(Suppl 1): i358.

  • Wu X.K., Wang Y.Y., Liu J.P., Liang R.N., Xue H.Y., Ma H.X., Shao X.G. and Ng E.H.Y., Randomized controlled trial of letrozole, berberine, or a combination for infertility in the polycystic ovary syndrome, Fertility and Sterility. 2016, 106(3): 757-765.

  • Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A double-blind randomised controlled trial on the effect of dehydroepiandrosterone on ovarian reserve markers, ovarian response and number of oocytes in anticipated normal ovarian responders, British Journal of Obstetrics and Gynaecology. 2016, 123: 1097–1105.

  • Yung SS, Lai SF, Lam MT, Lee VC, Li RH, Ho PC, Ng EH. Randomized, controlled, double-blind trial of topical lidocaine gel and intrauterine lidocaine infusion for pain relief during saline contrast sonohysterography. Ultrasound Obstet Gynecol 2016;47(1):17-21.

  • Yung SS, Lee VC, Chiu PC, Li HW, Ng EH, Yeung WS, Ho PC. The effect of 7 days of letrozole pretreatment combined with misoprostol on the expression of progesterone receptor and apoptotic factors of placental and decidual tissues from first-trimester abortion: a randomized controlled trial. Contraception 2016:93(4):323-30.

2015
  • Chai J, Lee VCY, Yeung TW., Li RHW, Ho PC and Ng EHY Live birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment. PLoS One 2015 Mar 6;10(3):e0119149.

  • Chan CHY, Chan THY, Chan CLW, Ng EHY and Ho PC. Diagnostic ambiguity and psychosocial distress among Chinese women with idiopathic and non-idiopathic infertility. Illness, Crisis & Loss 2015, 23(1): 45-48.

  • Chow JFC, Yeung WSB, Lee VCY, Lau EYL, Ho PC and Ng EHY Experience of more than 100 preimplantation genetic diagnosis cycles for monogenetic diseases using whole genome amplification and linkage analysis in a single centre. Hong Kong Medical Journal 2015, 21(4): 299-303.

  • Kottawatta KS, So KH, Kodithuwakku SP, Ng EH, Yeung WS, Lee CKF. MicroRNA-212 Regulates the Expression of Olfactomedin 1 and C-Terminal Binding Protein 1 in Human Endometrial Epithelial Cells to Enhance Spheroid Attachment In Vitro. Biol Reprod 2015 Nov;93(5):109.

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  • Lam KW, Li RHW, Ng EHY, Ho PC and Yeung WSB., Semen analysis - what a clinician should know. Journal of Paediatrics, Obstetrics and Gynaecology Singapore 2015, Jan: 37-44.

  • Lau KK, Ng EH, Tso YM, Mak CM. Halt hereditary tragedy by bridging the gap between knowledge and application of technology. Hong Kong Med J 2015 Apr;21(2):188-90.

  • Lee VC, Chow JF, Lau EY, Yeung WS, Ho PC, Ng EH. Comparison between fluorescent in-situ hybridisation and array comparative genomic hybridisation in preimplantation genetic diagnosis in translocation carriers. Hong Kong Med J. 2015 Feb;21(1):16-22. doi: 10.12809/hkmj144222. Epub 2014 Oct 24. [PubMed]

  • Lee YL, Fong SW, Chen AC, Li T, Yue C, Lee CL, Ng EH, Yeung WS, Lee KF.Establishment of a novel human embryonic stem cell-derived trophoblastic spheroid implantation model. Hum Reprod. 2015 Sep 7. pii: dev223. [Epub ahead of print]

  • Li HW, Liao SB, Chiu PC, Yeung WS, Ng EH, Cheung AN, Tang F, O WS. Effects of adrenomedullin on the expression of inflammatory cytokines and chemokines in oviducts from women with tubal ectopic pregnancy: an in-vitro experimental study. Reprod Biol Endocrinol. 2015 Nov 5;13(1):120. [Medline]

  • Li L, Li C, Pan P, Chen X, Wu X, Ng EH, Yang D. A Single Arm Pilot Study of Effects of Berberine on the Menstrual Pattern, Ovulation Rate, Hormonal and Metabolic Profiles in Anovulatory Chinese Women with Polycystic Ovary Syndrome. PLoS One 2015 Dec 8;10(12):e0144072.

  • Li RHW, Lam KSL, Tam S, Lee VCY, Yeung TWY, Cheung PT, Yeung WSB, Ho PC and Ng EHY. Screening for dysglycaemia by oral glucose tolerance test should be recommended in all women with polycystic ovary syndrome. Human Reproduction 2015, 30(9): 2178-2183.

  • So KH, Kodithuwakku SP, Kottawatta KS, Li RH, Chiu PC, Cheung AN, Ng EH, Yeung WS, Lee KF.Human chorionic gonadotropin stimulates spheroid attachment on fallopian tube epithelial cells through the mitogen-activated protein kinase pathway and down-regulation of olfactomedin-1. Fertil Steril. 2015 May 18. pii: S0015-0282(15)00304-0. doi: 10.1016/j.fertnstert.2015.04.030. [Epub ahead of print]

  • Wan HLT, Hui PW, Li RHW and Ng EHY. Obstetric outcomes in women with polycystic ovary syndrome and isolated polycystic ovaries undergoing in vitro fertilization: a retrospective cohort analysis. Journal of Maternal and Fetal Neonatal Medicine 2015, 28: 475-478.

  • Wang B, Ye TM, Lee KF, Chiu PC, Pang RT, Ng EH, Yeung WS.Annexin A2 Acts as an Adhesion Molecule on the Endometrial Epithelium during Implantation in Mice. PLoS One. 2015 Oct 7;10(10):e0139506. [Medline]

  • Yeung TWY, Chai J, Li RHW, Lee VCY, Ho PC and Ng EHY. Reply: Endometrial injury and reproductive outcomes: there's more to this story than meets the horse's blind eye. Human Reproduction 2015, 3: 749-750.

  • Zheng Y, Stener-Victorin E, Ng EHY, Li J, Wu X and Ma H. How does acupuncture affect insulin sensitivity in women with polycystic ovary syndrome and insulin resistance? Study protocol of a prospective pilot study. British Medical Journal Open 2015, 5(4): e007757-e007757.

2014
  • Chai J and Ng EHY. Evidence-based investigations for subfertility. Journal of Paediatrics, Obstetric & Gynaecology. 2014, 40(3): 125-131.

  • Chai J, Yeung TWY, Lee VCY, Li RHW, Lau EYL, Yeung WSB, Ho PC and Ng EHY. Live birth rate, multiple pregnancy rate, and obstetric outcomes of elective single and double embryo transfers: Hong Kong experience. Hong Kong Medical Journal 2014, 20(2):102-106.

  • Chai J, Yeung WY, Lee CY, Li HW, Ho PC, Ng HY. Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism. Clin Endocrinol (Oxf). 2014 Jan;80(1):122-7. [PubMed]

  • Chai J, Yeung WYT, Lee VCY, Li RHW, Ho PC, Ng HYE. Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism.  Clin Endocrinol (Oxf) 2014; 82(1): 122-127.

  • Chow JF, Yeung WS, Lau EY, Lee VC, Ng EH, Ho PC. Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage. Reprod Biol Endocrinol. 2014 Nov 24;12:105. doi: 10.1186/1477-7827-12-105. [PubMed]

  • Glasier A, Gemzell-Danielsson K, Bouchard P, Genazzani AR, Al-Azzawi F, Berga S, Birkhaeuser M, Brincat M, De Melo NR, Foidart JM, Kenemans P, Lunenfeld B, Maruo T, Milewicz A, Naftolin F, Ng EH, Schindler A, Simon C, Simoncini T, Simpson E, Siseles N, Smetnik V, Tarlatzis B, von Schoultz B. (2014) ISGE statement on oral emergency contraception. Gynecological Endocrinology. 30,681-682.

  • Lai CWS, Yung SSF, Ng EHY. Endometrial vascularity is lower in pregnancies with pregnancy-induced hypertension or small-for-gestational age in livebirth after IVF. Ultrasound in Obstetrics & Gynecology. 2014: 44(4) 455-460. [PubMed]

  • Lee CL, Li K, Lam KK, Ng EH, Koistinen H, Seppälä M, Yeung WS, Chiu PC.Glycodelin-A treatment reduces the adverse effect of macrophage co-culture on human sperm motility. Mol Reprod Dev. 2014 Jun;81(6):482-3. doi: 10.1002/mrd.22331. Epub 2014 May 9. [Medline]

  • Lee VCY, Chow JFC, Lau EYL, Yeung WSB, Ho PC, Ng EHY. Live birth following double-factor pre-implantation genetic diagnosis for both reciprocal translocation and alpha-thalassaemia. Hong Kong Med J 2014 Jun;20(3):251-4.

  • Lee VCY, Li RHW, Chai J, Yeung TWY, Yeung WSB, Ho PC and Ng EHY. Effect of preovulatory progesterone elevation and duration of progesterone elevation on the pregnancy rate of frozen–thawed embryo transfer in natural cycles. Fertility and Sterility 2014, 101: 1288-1293.

  • Li HW, Liao SB, Yeung WS, Ng EH, O WS, Ho PC. Ulipristal acetate resembles mifepristone in modulating human Fallopian tube function.Hum Reprod. 2014 Aug 19. pii: deu210. [Epub ahead of print]

  • Li RHW, Lee VCY, Ho PC and Ng EHY. Ovarian sensitivity index is a better measure of ovarian responsiveness to gonadotrophin stimulation than the number of oocytes during in-vitro fertilization treatment. Journal of Assisted Reproduction and Genetics 2014, 31: 199-203.

  • Li RHW, Lee VCY, Lau EYL, Yeung WSB, Ho PC and Ng EHY. Cumulative live-birth rate in women with polycystic ovary syndrome or isolated polycystic ovaries undergoing in-vitro fertilisation treatment. Journal of Assisted Reproduction and Genetics 2014, 31: 205-211.

  • Li RHW, Lee VCY, Lau EYL, Yeung WSB, Ho PC and Ng EHY. Role of baseline antral follicle count and anti-Mullerian hormone in the index stimulation cycle of IVF treatment in predicting outcome of subsequent frozen-thawed embryo transfers. Gynecological Endocrinology 2014 30: 490-493.

  • Li RHW, Lee VCY, Lau EYL, Yeung WSB, Ho PC, Ng EHY. Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-mullerian hormone and antral follicle count measurements: a retrospective study.  PLoS One 014;9(10):e108493.

  • Li RHW, Liao S., Yeung WSB, Ng EHY, O WS and Ho PC. Ulipristal acetate resembles mifepristone in modulating human Fallopian tube function. Human Reproduction 2014 29: 2156-2162.

  • Ng EHY, Li RHW, Chen L, Lan VT, Tuong HM, Quan S.  A randomized double blind comparison of atosiban in patients undergoing IVF treatment.  Hum Reprod 2014;29(12):2687-2694.

  • Seto MT, Yeung TWY, Li RHW, Ng EHY. Comparison of on-going pregnancy rates and multiple pregnancy rates of intrauterine insemination with ovarian stimulation using the clomiphene citrate versus gonadotrophin protocols. Hong Kong J Gynaecol Obstet Midwifery 2014; 14:89-92

  • So CC, Chiang AK, Kan A, Lee V, Ng E. (2014) Beta thalassaemia intermedia due to silent alpha globin gene quadruplication in an infant. Pathology. 2014 46,570-572.

  • Wang Q, Chow JF, Yeung WS, Lau EY, Lee VC, Ng EH, Ho PC. (2014) Preimplantation genetic diagnosis using combined strategies on a breast cancer patient with a novel genomic deletion in BRCA2. Journal of Assisted Reproduction & Genetics 2014;31(12):1719-26

  • Xiang L., Chan RWS, Ng EHY and Yeung WSB. Slow-cycling mesenchymal stromal cells in human endometrium possess common hallmark somatic stem cell properties Stem Cell Research & Therapy. 2014, 5: 84.

  • Yeung TWY, Chai J, Li RHW, Lee VCY, Ho PC and Ng EHY. A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders. Fertility and Sterility 2014, 102: 108-115.e1.

  • Yeung TWY, Chai J, Li RHW, Lee VCY, Ho PC, Ng EHY. The effect of endometrial injury on ongoing pregnancy rate in unselected subfertile women undergoing in vitro fertilization: a randomized controlled trial. Hum Reprod 2014; 29(11): 2474-2481.

2013
  • Lee VC, Gao J, Lee KF, Ng EH, Yeung WS, Ho PC. The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta. Hum Reprod 2013 Nov;28(11):2912-9.[PubMed]

  • Lee VC, Li RH, Ng EH, Yeung WS, Ho PC. Luteal phase support does not improve the clinical pregnancy rate of natural cycle frozen-thawed embryo transfer: a retrospective analysis. Eur J Obstet Gynecol Reprod Biol. 2013 Jul;169(1):50-3. [PubMed]

  • Li HW, Lee VC, Lau EY, Yeung WS, Ho PC, Ng EH. Role of baseline antral follicle count and anti-Mullerian hormone in prediction of cumulative live birth in the first in vitro fertilisation cycle: a retrospective cohort analysis. PLoS One. 2013 Apr 23;8(4):e61095. [PubMed]

  • O WS, Li HWR, Liao SB, Cheung ANY, Ng EHY, Yeung WSB, Ho JC, Tang F. The decreases in adrenomedullin and ciliary beat frequency in the nasal epithelium in tubal pregnancy Fertil Steril (2013 Aug;100(2):459-463 [PubMed]

  • Yeung TW, Li RH, Lee VC, Ho PC, Ng EH. A randomized double-blinded placebo-controlled trial on the effect of dehydroepiandrosterone for 16 weeks on ovarian response markers in women with primary ovarian insufficiency. J Clin Endocrinol Metab. 2013 Jan;98(1):380-8. [PubMed]

2012
  • Broeze KA, Opmeer BC, Coppus SF, Van Geloven N, Den Hartog JE, Land JA,Van der Linden PJQ, Ng EHY, Van der Steeg JW, Steures P, Van der Veen F, Mol BW. (2012) Integration of patient characteristics and the results of Chlamydia antibody testing and hysterosalpingography in the diagnosis of tubal pathology: an individual patient data meta-analysis. Human Reproduction 27, 2979-2990.

  • Chan CHY, Chan CLW, Ng EHY, Ho PC, Lee GL, Hui CWH. Incorporating spirituality in psychosocial group intervention for women undergoing in vitro fertilization: A prospective randomized controlled study. Psychology and Psychotherapy. 2012, 85(4): 356-373. 

  • Gao J, Zuo Y, So KH, Yeung WSB, Ng EHY, Lee KF. Electroacupuncture enhances spermatogenesis in rats after scrotal heat treatment. Spermatogenesis. 2012;2(1):53-62. [Medline]

  • Ko JK, Wan HL, Ngu SF, Cheung VY, Ng EH. Cesarean scar molar pregnancy. Obstet Gynecol. 2012 Feb;119(2 Pt 2):449-51. [PubMed]

  • Kodithuwakku SP, Pang RT, Ng EH, Cheung AN, Horne AW, Ho PC, Yeung WS, Lee KF. Wnt activation downregulates olfactomedin-1 in Fallopian tubal epithelial cells: a microenvironment predisposed to tubal ectopic pregnancy. Lab Invest. 2012;92(2):256-64. [Medline]

  • Lee CL, Lam EY, Lam KK, Koistinen H, Seppälä M, Ng EH, Yeung WS, Chiu PC. Glycodelin-A stimulates interleukin-6 secretion by human monocytes and macrophages through L-selectin and the extracellular signal-regulated kinase pathway. J Biol Chem. 2012 Oct 26;287(44):36999-7009. [PubMed]

  • Lee VC, Yeung TW, Tang OS, Ng EH, Yeung WS, Ho PC. Effect of letrozole on uterine artery Doppler flow indices prior to first-trimester termination of pregnancy: a randomized controlled trial. Ultrasound Obstet Gynecol. 2012 Oct;40(4):392-7. [PubMed]

  • Lee VCY, Ng EHY, Ho PC. (2012) Male infertility. Journal of Paediatrics, Obstetrics and Gynaecology, Sept-Oct, 213-220.

  • Lee YL, Peng Q, Fong SW, Chen AC, Lee KF, Ng EH, Nagy A, Yeung WS. Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways. PLoS One. 2012;7(9):e45633. [Medline]

  • Li HW, Ng EH, Wong BP, Anderson RA, Ho PC, Yeung WS. Correlation between three assay systems for anti-Müllerian hormone (AMH) determination. J Assist Reprod Genet. 2012 Dec;29(12):1443-6.

  • Li J, Wang W, Liang H, Dong H, Li Y, Ng EHY, Wu X (2012). Biophysical Characteristics of Meridians and Acupoints: A Systematic Review. Evidence-Based Complementary and Alternative Medicine 2012 (2012), Article ID 793841

  • Li RHY and Ng EHY. (2012) Management of anovulatory infertility. Best Practice & Research Clinical Obstetrics and Gynaecology 26, 757-768.

  • Liao SB, Li HW, Ho JC, Yeung WS, Ng EH, Cheung AN, Tang F, O WS. Possible role of adrenomedullin in the pathogenesis of tubal ectopic pregnancy. J Clin Endocrinol Metab. 2012 Jun;97(6):2105-12. [PubMed]

  • Liu WM, Pang RT, Cheong AW, Ng EH, Lao K, Lee KF, Yeung WS. Involvement of microRNA lethal-7a in the regulation of embryo implantation in mice. PLoS One. 2012;7(5):e37039. [Medline]

  • Ng EHY and Ho PC. (2012) Preface Best Practice & Research Clinical Obstetrics and Gynaecology 26, 727.

  • Yeung TWY, Lee CYV, Li HWR, Ng EHY. HKCOG guidelines: induction of ovulation. Journal of Paediatrics, Obstetrics and Gynaecology 2012;Jan/Feb, 5-31.

  • Yeung TWY, Lee VCY, Ng EHY, Ho PC. A pilot study on the use of a 7-day course of letrozole followed by misoprostol for the termination of early pregnancy up to 63 days. Contraception, 2012 Dec;86(6):763-9. [PubMed]

2011
  • Broeze KA, Opmeer BC, Coppus SF, Van Geloven N, Alves MF, Anestad G, Bhattacharya S, Allan J, Guerra-Infante MF, Den Hartog JE, Land JA, Idahl A, Van der Linden PJ, Mouton JW, Ng EH, Van der Steeg JW, Steures P, Svenstrup HF, Tiitinen A, Toye B, Van der Veen F, Mol BW. Chlamydia antibody testing and diagnosing tubal pathology in subfertile women: an individual patient data meta-analysis. Hum Reprod Update. 2011 May-Jun;17(3):301-10. [PubMed]

  • Broeze KA, Opmeer BC, Van Geloven N, Coppus SF, Collins JA, Den Hartog JE, Van der Linden PJ, Marianowski P, Ng EH, Van der Steeg JW, Steures P, Strandell A, Van der Veen F, Mol BW. Are patient characteristics associated with the accuracy of hysterosalpingography in diagnosing tubal pathology? An individual patient data meta-analysis. Hum Reprod Update. 2011 May-Jun;17(3):293-300. [PubMed]

  • Chai J, Lee KF, Ng EH, Yeung WS, Ho PC. Ovarian stimulation modulates steroid receptor expression and spheroid attachment in peri-implantation endometria: studies on natural and stimulated cycles. Fertil Steril. 2011 Sep;96(3):764-8. [Medline]

  • Chan RW, Ng EH, Yeung WS. Identification of cells with colony-forming activity, self-renewal capacity, and multipotency in ovarian endometriosis. Am J Pathol. 2011 Jun;178(6):2832-44.14. [PubMed]

  • Kodithuwakku SP, Ng PY, Liu Y, Ng EHY, Yeung WSB, Ho PC, Lee KF. Hormonal regulation of endometrial olfactomedin expression and its suppressive effect on spheroid attachment onto endometrial epithelial cells. Hum Reprod 2011;26:167-175. [Medline]

  • Lee VC, Chan CC, Ng EH, Yeung WS, Ho PC. Sequential use of letrozole and gonadotrophin in women with poor ovarian reserve: a randomized controlled trial. Reprod Biomed Online. 2011 Sep;23(3):380-8.

  • Lee VC, Ng EH, Yeung WS, Ho PC. Misoprostol with or without letrozole pretreatment for termination of pregnancy: a randomized controlled trial. Obstet Gynecol. 2011 Feb;117(2 Pt 1):317-23 [PubMed]

  • Lee VC, Tang OS, Ng EH, Yeung WS, Ho PC. A pilot study on the use of letrozole with either misoprostol or mifepristone for termination of pregnancy up to 63 days. Contraception. 2011 Jan;83(1):62-7.

  • Lee VC, Tang OS, Ng EH, Yeung WS, Ho PC. A prospective double-blinded, randomized, placebo-controlled trial on the use of letrozole pretreatment with misoprostol for second-trimester medical abortion. Contraception. 2011 Dec;84(6):628-33.

  • Lee VC, Yung SS, Li RH, Watzer B, Schweer H, Ng EH, Ho PC. A randomized comparison of pharmacokinetics of a single vaginal dose of dry misoprostol or misoprostol moistened with normal saline or with acetic acid. Hum Reprod. 2011 Nov;26(11):2981-7. [PubMed]

  • Li HWR, Yeung WSB, Lau EY, Ho PC, Ng EHY. Evaluating the performance of serum antimullerian hormone concentration in predicting the live birth rate of controlled ovarian stimulation and intrauterine insemination. Fertil Steril. 2010;94:2177-81. [PubMed]

  • Li RHW, Anderson RA, Yeung WS, Ho PC, Ng EH. Evaluation of serum antimullerian hormone and inhibin B concentrations in the differential diagnosis of secondary oligoamenorrhea. Fertil Steril. 2011 Sep;96(3):774-9. [PubMed]

  • Li RHW, Gebbie AE, Wong RWS, Ng EHY, Glasier AF, Ho PC. The use of sex hormones in women with rheumatological diseases. Hong Kong Med J 2011;17(6):487-491.

  • Li RHW, Lo SST, Ng EHY, Ho PC. An update on emergency contraception. J Paediat, Obst & Gyna 2011;36:81-88.

  • Li RHW, Ng EHY, Ho PC. Handbook on Managing Infertility (Meeting the Challenges in Low-Resource Settings) - Asia and Oceania Federation of Obstetrics and Gynaecology. Polycystic Ovary Syndrome and Infertility 2011;11:105-111.

  • Li RHW, Wong GCY, Yeung WSB, Ho PC, Ng EHY. Serum anti-mullerian hormone level is not altered in women using hormonal contraceptives. Contraception 2011;83:582-585.

  • Li Y, Ng EHY, Stener-Victorin E, Hou L, Wu T, Han F, Wu X. (2011) Polycystic ovary syndrome is associated with negatively variable impacts on domains of health-related quality of life: evidence from a meta-analysis. Fertil Steril, 96, 452-458.

  • Ng EHY. Author's reply: acupuncture improve pregnancy rate in sub-fertile women undergoing frozen-thawed embryo transfer cycles? Focus on Alternative and Complementary Therapy2011;16:138. 

2010
  • Lee KF, Lee YL, Chan RWS, Cheong AWY, Ng EHY, Ho PC, Yeung WSB. Up-regulation of endocrine gland-derived vascular endothelial growth factor but not vascular endothelial growth factor in human ectopic endometriotic tissue, Fertility and Sterility. 2010;93:1052-1060. (Publication No. : 175168)

  • Lee VCY, Ng EHY, Ho PC. Issues in second trimester induced abortion (medical/surgical methods). Best Pract Res Clin Obstet Gynaecol. 2010;24:517-27.

  • Lee VCY, Ng EHY, Yeung WSB, Ho PC. Impact of positive hepatitis B surface antigen on the outcome of IVF treatment. Reprod Biomed Online 2010;21:712-7.

  • Li HWR, Hui PW, Tang MHY, Lau ET, Yeung WSB, Ho PC, Ng EHY. Maternal serum anti-Mullerian hormone level is not superior to chronological age in predicting Down syndrome pregnancies. Prenat Diagn. 2010;30:320-4.

  • Li HWR, Liao S, Chiu PCN, Tam WW, Ho JCM, Ng EHY, Ho PC, Yeung WSB, Tang F, O WS, Expression of adrenomedullin in human oviduct, its regulaton by the hormonal cycle and contact with spermatozoa, and its effect on ciliary beat frequency of the oviductal epithelium, Journal of Clinical Endocrinology and Metabolism. 2010;95:E18-E25. (Publication No. : 182871) 

  • Li HWR, Ng EHY, Ho PC. Clinical applications of misoprostol in gynaecology.  J Paed Obstet Gynaecol 2010;36: 81-88.

  • Liu Y, Kodithuwakku SP, Ng PY, Chai J, Ng EH, Yeung WS, Ho PC, Lee KF. Excessive ovarian stimulation up-regulates the Wnt-signaling molecule DKK1 in human endometrium and may affect implantation: an in vitro co-culture study. Hum Reprod 2010;25:479-90. [PubMed]

  • Ng EH. Comment on Checa MA et al. J Assist Reprod Genet. 2010;27:65. 

  • Ng EHY, Ho PC. Ultrasound assessment of endometrial receptivity in in vitro fertilization treatment. DonaldSchool Journal of Ultrasound in Obstetrics and Gynecology 2010;4:179-188.

  • So EW, Ng EH. Acupuncture in reproductive medicine. Womens Health (Lond Engl). 2010;6:551-63.

  • So WS, Ng EHY, YY Wong, EYL Lau, WSB Yeung, Ho PC. Acupuncture for frozen-thawed embryo transfer cycles: a double-blind randomized controlled trial. Reproductive BioMedicine Online 2010;20,814-821.

  • von Hertzen H, Huong NTM, Piaggio G, Bayalag M, Cabezas E, Fang A, Gemzell-Danielsson K, Hinh ND, Mittal S, Ng EHY, Chaturachinda K, Pinter B, Puscasiu L, Savardekar L, Shenoy S, Tsertsvadze G, Tuyet HTD, Velasco A, Peregoudov A for the WHO Research Group on Post-ovulatory Methods of Fertility Regulation. Two doses and two routes of administration of misoprostol after mifepristone for termination of early pregnancy: a randomized controlled non-inferiority trial. BJOG: An International Journal of Obstetrics and Gynaecology 2010;117:1186-1196.

  • Yeung WS, Li RH, Cheung TM, Ng EH, Lau EY, Ho PC. Frozen-thawed embryo transfer cycles. Hong Kong Med J. 2009;15:420-6.

2009
  • Chai J, Tang OS, Hong QQ, Chen QF, Cheng LN, Ng E, Ho PC. A randomized trial to compare two dosing intervals of misoprostol following mifepristone administration in second trimester medical abortion. Hum Reprod. 2009 Feb;24(2):320-4. [PubMed]

2008
  • Liu Y, Lee KF, Ng EH, Yeung WS, Ho PC. Gene expression profiling of human peri-implantation endometria between natural and stimulated cycles. Fertil Steril. 2008 Dec;90(6):2152-64. doi: 10.1016/j.fertnstert.2007.10.020. Epub 2008 Jan 14. [PubMed]

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2007
  • Chiu PC, Chung MK, Koistinen R, Koistinen H, Seppala M, Ho PC, Ng EH, Lee KF, Yeung WS. Glycodelin-A interacts with fucosyltransferase on human sperm plasma membrane to inhibit spermatozoa-zona pellucida binding. J Cell Sci. 2007 Jan 1;120(Pt 1):33-44. [PubMed]

2004
  • Kan AS, Ng EH, Ho PC. (2004) The role and comparison of two techniques of paracervical block for pain relief during suction evacuation for first-trimester pregnancy termination. Contraception. 70, 159-63.

  • Lam KW, Pun TC, Ng EH, WongKS. (2004) Efficacy of preemptive analgesia for wound pain after laparoscopic operations in infertile women: a randomised, double-blind and placebo control study. BJOG. 111, 340-4. [PubMed]

Research Grants

  • Control of human decidual macrophage differentiation by glycodelin-A. University Grants Committee of Hong Kong (UGC) Research Grants Council (RGC) Earmarked Grant for Research 2011-2012 (Principal Investigator) HK$1,297,160 (2012-2014)
  • Role of SIRT1 in generation of mouse induced pluripotent stem cells. University Grants Committee of Hong Kong (UGC) Research Grants Council (RGC) Earmarked Grant for Research 2010-2011 (Principal Investigator) HK$1,050,000 (2011-2014)
  • Preimplantation genetic diagnosis of beta Thalassaemia and HLA typing using the whole genome amplification method. Children’s Thalassaemia Foundation (Principal Investigator) HK$200,000 (2011-2012)

Professional Activities

  • 2010-present: Chairman of the Research subcommittee, Hong Kong College of Obstetricians and Gynaecologists
  • 2008-present: Member of Health Services Subcommittee of Family Planning Association, Hong Kong
  • 2011-present: Council member of Family Planning Association, Hong Kong 
  • 2013-present: Chairman of the Subspecialty Board on Reproductive Medicine, Hong Kong College of Obstetricians and Gynaecologists

Awards and Honors

  • Young Investigator’s Award-- Li HWR, Wong CYG, Yeung WSB, Ho PC, Ng EHY. Anti-Mullerian hormone is a potentially useful test of ovarian function in progestogen-only contraceptive users. The 3rd Congress of Asia-Pacific Council on Contraception, 11-13 Jun 2010, Beijing, China. 
  • Best abstract Award-- Lee VCY, Ng EHY, Yeung WSB, Ho PC. A prospective double-blinded randomised placebo controlled trial on the use of misoprostol with or without letrozole pretreatment for termination of pregnancy up to 63 days of gestation. Presented at The 13th World Congress on Controversies in Obstetrics, Gynecology & Infertility, Berlin, Germany, 4-7, November, 2010.
  • “多囊卵巢綜合症「天癸失序」的病理機制” in collaboration with Heilongjiang University of Chinese Medicine being conferred a Second Class Award under the category of Natural Science Research Outstanding Achievement Award 2010.
  • The Young Investigator Award-- Chow JFC, Yeung WSB, Lau EYL, Li RHW, Ng EHY, Ho PC. (2011) Preimplantation genetic diagnosis of thalassemia using whole genome amplification and polymerase chain reaction. The 8th Conference of the Pacific Rim Society for Fertility and Sterility organized by the Pacific Rim Society for Fertility and Sterility and The Hong Kong Society for Reproductive Medicine, Hong Kong, 27-29 May 2011.
  • The Best Poster Award-- Chai J, Lee KF, Ng EHY, Yeung WSB, Ho PC. (2011) Steroid receptors expression pattern of peri-implantation endometrium between natural and stimulated cycles. The 8th Conference of the Pacific Rim Society for Fertility and Sterility organized by the Pacific Rim Society for Fertility and Sterility and The Hong Kong Society for Reproductive Medicine, Hong Kong, 27-29 May 2011. And Cheung CSY, Chan CHY, Ng EHY. (2011) Stress and anxiety-depression levels following early pregnancy loss: a comparison between women who conceived naturally and after assisted reproduction methods. The 8th Conference of the Pacific Rim Society for Fertility and Sterility organized by the Pacific Rim Society for Fertility and Sterility and The Hong Kong Society for Reproductive Medicine, Hong Kong, 27-29 May 2011.
  • “中醫生殖軸理論在多囊卵巢綜合征和輔助生殖中的轉化應用與發展”in collaboration with the Heilongjiang University of Chinese Medicine being conferred a First Class Award under the category of the Scientific and Technological Progress Award 2011.
  • 第四屆中國針灸學會科學技術獎一等獎--“女性生殖障礙的針刺療效機制”