Dr. S.F. NGU 吳庥慧醫生

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Clinical Associate Professor

MBBS (London), FRCOG, FHKCOG, FHKAM (O&G), Cert RCOG (Gynae Onc)

location Department of O&G, Queen Mary Hospital
phone (852)-2255-4517
fax (852)-2855-0947
email HKU Scholars Hub
email https://orcid.org/0000-0001-9314-5468
Research Interests
  • General Gynacology
  • Gynaecological Onocology
  • Ngu S.F., Chai Y.K.V., Choi K.M.C., Leung T.W., Li J., Kwok S.T.G., Chu M.Y.M., Tse K.Y., Cheung V.Y.T., Ngan H.Y.S. and Chan K.K.L., Diagnostic Performance of Risk of Malignancy Algorithm (ROMA), Risk of Malignancy Index (RMI) and Expert Ultrasound Assessment in a Pelvic Mass Classified as Inconclusive by International Ovarian Tumour Analysis (IOTA) Simple Rules., Cancers (Basel). . 2022, 14(3), 810.
  • Ng T.Y., Ngu S.F., Kam T.Y.D., Ng S.Y. and Lo P.L.B., First in-human trial and prospective case series of an articulated laparoscopic camera system in minimally invasive surgery in gynecology: an IDEAL stage 1 and 2a study., BMJ Surg Interv Health Technologies. 2022, 4.
  • Ngu S.F., Lau S.K., Li J., Wong C.Y.G., Cheung A.N.Y., Ngan H.Y.S. and Chan K.K.L., Human Papillomavirus Self-Sampling for Primary Cervical Cancer Screening in Under-Screened Women in Hong Kong during the COVID-19 Pandemic., Int J Environ Res Public Health.. 2022, 19(5), 2610.
  • Ngu S.F., A patient with newly diagnosed Stage III clear cell BRCA-mutated ovarian cancer treated with more than 2 years of PARPi maintenance therapy, MIMS Oncology. 2021, July - August 2021, 20-21.
  • Ngu S.F., Tse K.Y., Chu M.Y.M., Ngan H.Y.S. and Chan K.K.L., Olaparib dose re-escalation in ovarian cancer patients who experienced severe and/or uncommon adverse events: A case series., Asia Pac J Clin Oncol.. 2021, 17, 3-11. http://dx.doi.org/10.1111/ajco.13584
  • Ngu S.F., Ngan H.Y.S. and Chan K.K.L., Role of adjuvant and post-surgical treatment in gynaecological cancer, Best Practice & Research Clinical Obstetrics & Gynaecology. 2021. http://dx.doi.org/10.1016/j.bpobgyn.2021.09.001
  • Siu K.Y., JIANG Y., WANG J., Leung T.H.Y., Ngu S.F., Cheung A.N.Y., Ngan H.Y.S. and Chan K.K.L., PDK1 promotes ovarian cancer metastasis by modulating tumor-mesothelial adhesion, invasion, and angiogenesis via α5β1 integrin and JNK/IL-8 signaling, Oncogenesis. 2020, 9. http://dx.doi.org/10.1038/s41389-020-0209-0
  • Chan K.K.L., Liu S., Wei N., Ngu S.F., Chu M.Y.M., Tse K.Y., Lau S.K., Cheung A.N.Y. and Ngan H.Y.S., Primary HPV testing with cytology versus cytology alone in cervical screening—A prospective randomized controlled trial with two rounds of screening in a Chinese population , International Journal of Cancer. 2020. http://dx.doi.org/10.1002/ijc.32861
  • CHEN R., Yung M.H., XUAN Y., ZHAN S., LEUNG L.L., LIANG R., Leung T.H.Y., Yang H.J., Xu D., Sharma R., Chan K.K.L., Ngu S.F., Ngan H.Y.S. and Chan D.W., Targeting of lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases in ovarian cancer cells, Communications Biology. 2019, 2. http://dx.doi.org/10.1038/s42003-019-0508-1

  • CHEN K., Liu X., MAK S.L., Yung M.H., Leung T.H.Y., Xu D., Ngu S.F., Chan K.K.L., Yang H.J., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways , Theranostics. 2018, 8: 423-436. http://dx.doi.org/10.7150/thno.22377 (Publication No. : 284013)

  • Liu S., Chan K.K.L., Chu K.H., Wei N., Lau S.K., Ngu S.F., Chu M.Y.M., Tse K.Y., Ip P.C.P., Ng E.K.O., Cheung A.N.Y. and Ngan H.Y.S., Oncogenic microRNA signature for early diagnosis of cervical intraepithelial neoplasia and cancer, 2018. http://dx.doi.org/10.1002/1878-0261.12383(Publication No. : 294143)

  • Ngu S.F., Chu M.Y.M., Tse K.Y., Chan K.K.L., Ip P.C.P., Cheung A.N.Y. and Ngan H.Y.S., Role Of Lymphadenectomy And Vincristine, Actinomycin-D, and Cyclophosphamide Chemotherapy in Malignant Ovarian Germ Cell Tumors, European Journal of Gynaecological Oncology. 2018, 39(1): 63-69. http://dx.doi.org/10.12892/ejgo3763.2018 (Publication No. : 284270)

  • Tse K.Y., Chiu W.H.K., Chan K.K.L., Chu M.Y.M., Ngu S.F., Cheung A.N.Y., Ngan H.Y.S. and Ip P.C.P., A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors, American Journal of Clinical Pathology. 2018. http://dx.doi.org/10.1093/ajcp/aqy039 (Publication No. : 285802)

  • Yung M.H., Tang W.M., Cai C.H., Leung T.H.Y., Ngu S.F., Chan K.K.L., Xu D., Yang H.U.I.J.U.A.N., Ngan H.Y.S. and Chan D.W., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade, Theranostics. 2018, 8: 1270-1285. http://dx.doi.org/10.7150/thno.22536 (Publication No. : 284377)

  • Lee E.Y.P., PERUCHO J.A.U., Vardhanabhuti V., He J., Siu W.K.S., Ngu S.F., Mayr N.A., Yuh W.T.C., Chan Q. and Khong P.L., Intravoxel incoherent motion MRI assessment of chemoradiation-induced pelvic bone marrow changes in cervical cancer and correlation with hematological toxicity, Journal of Magnetic Resonance Imaging. 2017, 46: 1491-1498.

  • Ngu SF, Chu MM, Ip PP, Ngan HY. Vulvar Hidradenitis Suppurativa: Is the Mass Malignant? J Obstet Gynaecol Can. 2017 Mar 30. S1701-2163(16)39741-9.

  • Ngu SF, Wei N, Kwan TT, Chu MM, Tse KY, Chan KK, Ngan HY. Impact of different educational interventions on psychosocial well-being of women with a positive high-risk human papillomavirus and normal cervical cytology: a randomised trial. J Psychosom Obstet Gynaecol. 2017 Apr 10:1-10.

  • SF Ngu, N Wei, TTC Kwan, MMY Chu, KY Tse, KKL Chan, HYS Ngan. Impact of different educational interventions on psychosocial wellbeing of Hong Kong Chinese women with a positive high-risk human papillomavirus and normal cervical cytology. Journal of Psychosomatic Obstetrics & Gynecology 2017: 10: 1 – 10.

  • Agarwal Sharma R., Lee E.Y.P., Vardhanabhuti V., Khong P.L. and Ngu S.F., Unusual Case of Postmenopausal Diffuse Endometriosis Mimicking Metastastic Ovarian Malignancy, Clinical Nuclear Medicine. 2016, 41(2): e120-e122. http://dx.doi.org/10.1097/RLU.0000000000001038

  • Ngai F.W. and Ngu S.F., Family sense of coherence and family and marital functioning across the perinatal period, Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives. 2016, 7: 33-37.

  • Seto MT, Ip PPC, Ngu SF, Cheung ANY, Pun TC. Positive predictive value of endometrial polyps in Pipelle aspiration sampling: A histopathological study of 195 cases. Eur J Obstet Gynecol Reprod Biol. 2016 Apr 30;203:12-15.

  • Seto T.Y.M., Ip P.C.P., Ngu S.F., Cheung A.N.Y. and Pun T.C., Positive predictive value of endometrial polyps in Pipelle aspiration sampling: a histopathological study of 195 cases., Eur J Obstet Gynecol Reprod Biol.. 2016, 203: 12-15.

  • Yung SS, Ngu SF, Cheung VY. Late presentation of a variant of Herlyn-Werner-Wunderlich syndrome. Int J Gynaecol Obstet 2016:133(2):238-9.

  • Cheung KW, Ngu SF and Cheung VYT. Sonographic characteristics of the uterus in asymptomatic women after second-trimester medical termination of pregnancy. J Ultrasound Med 2015, 34(4): 611-6.

  • Ngai FW and Ngu SF. Predictors Of Maternal And Paternal Depressive Symptoms At Postpartum. J Psychosom Res 2015, 78(2): 156-61.

  • Ngu SF and Ngan HYS. Chemotherapy in pregnancy. Best Pract Res Clin Obstet Gynaecol 2015, http://dx.doi.org/10.1016/j.bpobgyn.2015.10.007

  • Ko JK, Seto MT, Ngu SF, Cheung VT. Urethral prolapse in a postmenopausal woman. Journal of Obstetrics and Gynaecology Canada. J Obstet Gynaecol Can 2014. Feb;36(2):105.

  • Ko JKY, Seto TYM, Ngu SF and Cheung VYT. Urethral Prolapse In A Postmenopausal Woman. J Obstet Gynaecol Canada 2014, 36(2): 105.

  • Lui MW, Ngu SF, Cheung VY. Mullerian cyst of the uterus misdiagnosed as ovarian cyst on pelvic sonography. J Clin Ultrasound. 2014 Mar-Apr;42(3):183-4.

  • Ngai FW and Ngu SF. Family Sense Of Coherence And Family Adaptation Among Childbearing Couples, Journal of Nursing Scholarship. 2014, 46: 82-90.

  • Ngai FW and Ngu SF. Predictors Of Family And Marital Functioning At Early Postpartum. J Adv Nurs. 2014, 70(11): 2588-97.

  • Ngu SF, Cheung VYT and Pun TC. Surgical Management of Adnexal Masses in Pregnancy. JSLS. 2014, 18(1): 71-75.

  • Cheung KW, Ngu SF, Lee CP. Fetal fibronectin test on Chinese women with symptoms of preterm labour: a pilot study. Hong Kong Med J. 2013 Oct;19(5):424-8. [PubMed]

  • Chia CF, Lai JH, Cheung PK, Kwong LT, Lau FP, Leung KH, Leung MT, Wong FC, Ngu SF. Dysmenorrhoea among Hong Kong university students: prevalence, impact, and management. Hong Kong Med J. 2013 Jun;19(3):222-8. [PubMed]

  • Lui MW, Ngu SF, Cheung VY. Mullerian cyst of the uterus misdiagnosed as ovarian cyst on pelvic sonography. J Clin Ultrasound. 2013 Aug 16. doi: 10.1002/jcu.22081. [Epub ahead of print] [PubMed]

  • Ngu SF, Ko JK, Cheung VY. Value of human chorionic gonadotropin levels in diagnosing cervical ectopic pregnancy. Acta Obstet Gynecol Scand. 2013 May;92(5):608-9. [PubMed]

  • Seto MT, Ngu SF, Cheung VY, Pun TC.Second trimester medical abortion in a woman with prior classical caesarean section and a uterine leiomyoma - A case report. Eur J Contracept Reprod Health Care. 2013 Oct;18(5):410-4. [PubMed]

  • Ko JK, Wan HL, Ngu SF, Cheung VY, Ng EH. Cesarean scar molar pregnancy. Obstet Gynecol. 2012 Feb;119(2 Pt 2):449-51. [PubMed]

  • Ngai FW, Ngu SF. Family sense of coherence and quality of life. Qual Life Res. 2012 Dec 9. [Epub ahead of print] [PubMed]

  • Ngai FW, Ngu SF. Psychometric properties of a Chinese version of the medical outcomes study family and marital functioning measures in Hong Kong Chinese childbearing families. Community Ment Health J. 2012 Oct;48(5):634-42. 

  • Ngu SF, Cheung VY, Pun TC. Randomized study of vaginoscopy and H Pipelle vs traditional hysteroscopy and standard Pipelle. J Minim Invasive Gynecol. 2012 Mar-Apr;19(2):206-11. [PubMed]

  • Ngai FW, Ngu SF. Translation and validation of a chinese version of the family sense of coherence scale in Chinese childbearing families. Nurs Res. 2011 Sep-Oct;60(5):295-301. [PubMed]

  • Ngu SF, Cheung VY. Non-tubal ectopic pregnancy. Int J Gynaecol Obstet. 2011 Dec;115(3):295-7. [PubMed]

  • Ngu SF, Cheung VY, Pun TC. Left upper quadrant approach in gynecologic laparoscopic surgery. Acta Obstet Gynecol Scand. 2011 Dec;90(12):1406-9. [PubMed]

  • Ngu SF, Cheung VY. Vulvar endometriosis. J Obstet Gynaecol Can. 2011 Sep;33(9):891.

  • Ngu SF, Cheung VYT. An update on the management of acute pelvic inflammatory disease. The Hong Kong Medical Diary. 2011 Oct;16(10):9-11.

  • Ngu SF, Wan T, Tam YS, Cheung VY. Torsion of a tumor within an accessory ovary. Obstet Gynecol 2011;117(2 Pt 2):477-8. [PubMed]