Dr. D. LIU 劉東騰博士
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Research Assistant Professor BSc, PhD (Xiamen Universtiy) |
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Department of Obstetrics and Gynaecology (L7, Laboratory Block) |
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https://orcid.org/0000-0002-9335-6940 |
Research Interests
- Meiotic recombination and sex chromosome behavior in male meiosis
- Germ cell development and human reproductive health
- Ovarian stromal factors involved in follicle activation
- Drug repurposing for the treatment of patients with POI or DOR
Publications
2026
- Lin Z, Li Y, Zhao Y, Liu D, Deng S, Gu J, Li Y, Zhao X, Wu P, Xiao Y, Su J, Sun Y, Zhang Y, Lee YL, Sato Y, Zeng H, Lu H, Zhang J, Ko JKY, Zhao J, Kawamura K, Ng EHY, Jiang S, Li Y, Xia X, Chan KKL, Yeung WSB, Wang TR, Liu K. Antifibrotic drug finerenone restores fertility in premature ovarian insufficiency. Science. 2026 Feb 5;391(6785):eadz4075. doi: 10.1126/science.adz4075. Epub 2026 Feb 5. PMID: 41643022.
2025
- Liu D, Zhang Y, Li D, Jiang B, Zhao X, Li Y, Lin Z, Zhao Y, Hu Z, Deng S, Li Z, Lu H, Chan KKL, Yeung WSB, Kaldis P, Yao C, Wang H, Chow LT, Liu K. Speedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization. EMBO J. 2025 Oct;44(19):5509-5536. doi: 10.1038/s44318-025-00528-8. Epub 2025 Aug 18. PMID: 40826181; PMCID: PMC12488978.
2024
- Lin Z, Li D, Zheng J, Yao C, Liu D, Zhang H, Feng H, Chen C, Li P, Zhang Y, Jiang B, Hu Z, Zhao Y, Shi F, Cao D, Rodriguez-Wallberg KA, Li Z, Yeung WSB, Chow LT, Wang H, Liu K. The male pachynema-specific protein MAPS drives phase separation in vitro and regulates sex body formation and chromatin behaviors in vivo. Cell Rep. 2024 Jan 23;43(1):113651. doi: 10.1016/j.celrep.2023.113651. Epub 2024 Jan 3. PMID: 38175751.
2022
- Zhao Y., ZHANG Y., Liu D., Feng H., Wang X., Su J., Yao Y., Ng E.H.Y., Yeung W.S.B., Li R.H.W., Rodrigues-Wallberg K.A. and Liu K., Identification of curcumin as a novel potential drug for promoting the development of small ovarian follicles for infertility treatment, PNAS Nexus. 2022.
2021
- Li M., ZHENG J., Li G., Lin Z., LI D., Liu D., Feng H., Cao D., Ng E.H.Y., Li R.H.W., Han C., Yeung W.S.B., Chow L.T., Wang H. and Liu K., The male germline-specific protein MAPS is indispensable for pachynema progression and fertility, Proceedings of the National Academy of Sciences. 2021, 118, e2025421118. http://dx.doi.org/10.1073/pnas.2025421118
